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May 16, 2019 posted by

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Serum levels of cartilage oligomeric matrix protein COMP correlate with radiographic progression of knee osteoarthritis. Monoclonal Antibody Other names: It has been proposed that COMP molecules are important for maintaining the properties and integrity of collagen network. OA and RA are a common disease causing pain and disability in a significant proportion of the adult population and early diagnostics of these diseases is very important for future therapy. The antibody is lyophilized in 0. Serum cartilage oligomeric matrix protein and clinical signs and symptoms of potential pre-radiographic hip and knee pathology. Ethnic and sex differences in serum levels of cartilage oligomeric matrix protein:

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Monoclonal Antibody Other names: Serum cartilage oligomeric matrix protein reflects the presence of clinically diagnosed synovitis in patients with knee osteoarthritis. Serum levels of cartilage oligomeric matrix protein frer elevated in rheumatoid arthritis, but not in inflammatory rheumatic diseases such as psoriatic arthritis, reactive arthritis, Raynaud’s syndrome, scleroderma, systemic lupus erythematosus, vasculitis and Sjogren’s syndrome.

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Measurement of cartilage oligomeric matrix protein COMP in normal and diseased equine synovial fluids. In this case clarify the solution by centrifugation. COMP is not only cartilage-derived but was found widely in other tissues, including synovium and tendon.

Results have demonstrated an association of increasing serum COMP levels with progressive destruction of articular cartilage monitored radiographically.

Monoclonal antibodies to human cartilage oligomeric matrix protein: Ethnic and sex differences in serum levels of cartilage 12d4 matrix protein: Biochemical markers of bone and cartilage remodeling in prediction of longterm progression of knee osteoarthritis.

Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. Most published studies have shown that serum levels of COMP provide important information about metabolic changes occurring in the cartilage matrix in joint disease.

Research topic Bone and cartilage metabolism Summary Cartilage oligomeric matrix protein COMPalso designated thrombospondin 5 TSP 5is non-collagenous glycoprotein and is a member of the thrombospondin family of extracellular proteins.

Serum cartilage oligomeric matrix protein and clinical signs and symptoms of potential pre-radiographic hip and knee pathology.

Serum levels of cartilage oligomeric matrix protein COMP correlate with radiographic progression of knee osteoarthritis. OA and RA are a common disease causing pain and disability in a significant proportion of the adult population and early diagnostics of these diseases is very important for future therapy.

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Cartilage Oligomeric Matrix Protein Human, Mouse Monoclonal Antibody, Clone: 12C4 | BioVendor

Characterization of monoclonal antibodies recognizing different fragments of cartilage oligomeric matrix protein in human body fluids. Please select your region to see available products and prices.

The antibody is lyophilized in 0. It has been proposed that COMP molecules are important for maintaining the properties and integrity of collagen network.

Cartilage Oligomeric Matrix Protein Human, Mouse Monoclonal Antibody, Clone: 12C4

Cartilage oligomeric matrix protein COMPalso designated thrombospondin 5 TSP 5is non-collagenous glycoprotein and is a member of the thrombospondin family of extracellular proteins. In addition COMP may have a storage and delivery function for hydrophobic cellsignaling molecules such as vitamin D.

These studies describe that serum COMP level correlated with cartilage degradation and is a potential prognostic marker in inflammatory joint diseases such as osteoarthritis OA and rheumatoid arthritis RA.